The Newest Alzheimers Research

 
 

"All in all, we are faced obviously with a peculiar disease process," physician Alois Alzheimer wrote in 1901. After performing an autopsy on one of his patients, the German doctor concluded that the memory loss, disorientation, impaired speech and delusions were caused by brain shrinkage, widespread dead cells and protein deposits. He began to learn more about Alzheimers, but just fifteen years later, Alois Alzheimer died, never knowing that a whole branch of Alzheimers research would develop based on his work.

Some of the newest Alzheimers research has focused on brain cell connectors. A new study done by Northwestern University's Feinberg School of Medicine found a connection between signs of Alzheimers and a brain protein called kalirin-7. "We already knew that kalirin controlled the synapses," lab researcher Peter Penzes explains. "But now we understand how it works and that it could be responsible for memory storage. Kalirin acts like a volume dial, making the synapses stronger. This suggests that a drug that would stimulate kalirin could improve memory or delay the progression of memory loss." The next step in this Alzheimers brain research is, of course, human clinical trials.

Australian scientists feel they have made a breakthrough in Alzheimers research. A clinical trial showed that a new medication reduces levels of the "amyloid" brain protein, which behaves strangely in Alzheimers patients - dividing irregularly and leaving sticky toxic clumps that kill neurons. The "PBT2" Alzheimers drug stops beta amyloid from combining with other materials to form plaques. "We found we were able to remove the pathology of Alzheimer's disease in animal models," said Professor Ashley Bush, of the University of Melbourne. "In human patients, the results from the 12 week trial were remarkable. We can only imagine that with a longer trial, the effect will be even stronger." If successful, then the drug could be available as early as 2011. 

While there has been no definitive Alzheimers prevention found by research, doctors say that exercise, which raises your heart rate for at least 30 minutes several times per week diminishes your risk of Alzheimers. In animal experiments at the University of Chicago, they found that signs of Alzheimers were less visible in mice that had frequent exercise. In fact, active mice who exercised had 50-80% less plaque deposits in the brain than sedentary mice. "Regular physical exercise is probably the best means we have of preventing Alzheimers disease today," says Dr. Ronald Petersen, director of the Alzheimers Research Center at the Mayo Clinic. He added, "It's better than medications, better than intellectual activity, better than supplements and diet."

Alzheimers Research - Google News
Alzheimers Research - Google News
Alzheimers Research - Google News

Alzheimer's research hit by lack of brains - Scotsman

BBC News

Alzheimer's research hit by lack of brains
Scotsman, United Kingdom - Jan 6, 2009
Meanwhile, only 30 brains can be used at Oxford University to research Alzheimer's. Academics looking to understand the disease better say they want some ...
Appeal for research brain donors BBC News
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British researchers short of brains Nature.com (subscription)
The Press Association - Register
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Nampa couple raises thousands of dollars for Alzheimer's research ... - Idaho...

Nampa couple raises thousands of dollars for Alzheimer's research ...
IdahoStatesman.com, ID - Jan 6, 2009
A Nampa couple has raised more than $7500 for Alzheimer's research at Boise State University during a five-week fund raiser at Treasure Valley businesses. ...

Alzheimer's research at UM flags key genes - MiamiHerald.com

PsychCentral.com

Alzheimer's research at UM flags key genes
MiamiHerald.com, FL - Jan 5, 2009
New research by the University of Miami zeroes in on the culprit genes in Alzheimer's disease. But more work is needed to predict, diagnose and treat the ...
Study: Vitamin D Linked To Alzheimer?s Gene Looking Fit
UM Genetic Researchers Release New Findings On Alzheimer's Disease Medical News Today (press release)
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Google Video - Alzheimers Research

Alzheimers Research Updates

Click 'more' for details. The information below is an excerpt from the library on the Norml web site. Please excuse Spelling Error on video Open ...

www.youtube.com


Alzheimer's Research Continues

Watch this video about Alzheimer's on HowStuffWorks. Alzheimer's disease is now estimated to affect more than five million people in the U.S. and ...

videos.howstuffworks.com


Alzheimer's Research and Basic Science of Aging: Is There a ...

Alzheimer's disease, which afflicts more than 4 million Americans, continues to enjoy an abundant amount of media, public and government attention ...

video.google.com


 
 
 
 
   
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